![]() Originally developed by Roche and sold under license by Boehringer Ingelheim in India as Metalyse, tenecteplase is used as a treatment for heart attack but is not approved anywhere as an ischemic stroke treatment-other than in India. If you could reopen the blood supply to the brain within a few minutes everybody would completely recover from a stroke, he added.Plans by Indian drugmaker Gennova to launch its generic clot-buster tenecteplase as a treatment for stroke in India are "incomprehensible," according to a leading stroke expert. Therefore, the sooner a patient gets treatment the less severe the stroke. Treatment for stroke such as thrombectomy or thrombolysis work to reopen the blood vessels that have been blocked in the brain and Dr Thornton added that for every minute lost in reopening the blood vessels the more likely it is that you will have a severe and permanent stroke. However, the brain has the capacity to change the circulation for a short period, allowing for the possibility of recovery if the blood vessel is opened up within the first few hours.” Brain cells depend on blood for oxygen if you cut off the oxygen supply then the brain cells will die and for most people brain cell death starts to take effect almost straight away. This change which is initially small and reversible starts to become permanent as the minutes tick by. “Time is critical when it comes to acute ischaemic stroke because as soon as the vessel is blocked off you start to get cell death, you start to damage the brain tissue. Studies have shown that in eligible patients, thrombectomy can reduce the death rate from stroke by half and almost doubles the rate of recovery to complete independent living.Īlmost half of patients who received a thrombectomy in Ireland in 2019 returned to living a fully independent life.ĭr John Thornton, Consultant Interventional Radiologist and Director of the National Thrombectomy Service (NTS) at Beaumont Hospital in Dublin. Some patients treated with thrombectomy will make a full recovery and will live several or many years with a completely normal life and other patients will have a partial recovery but unfortunately when the treatment isn’t successful, or it is too late, some patients don’t gain as much benefit. On average for every minute that you save in removing the clot you gain a week of healthy living post stroke, so thrombectomy can have quite a dramatic effect. Patients need to be treated as fast as possible, as with every short interval of time that passes they may become unsuitable for treatment or not get as good a recovery, if the stroke becomes permanent. Thrombectomy is carried out in two specialist centres in Ireland at Beaumont Hospital in Dublin and Cork University Hospital in Cork. Unlike thrombolysis which uses drugs to try and dissolve a blood clot, thrombectomy is a radiologically guided interventional procedure where doctors use specialist equipment to mechanically remove the clot from the brain and restore blood supply. It is estimated that approximately 10 to 20 per cent of stroke patients would have this type of stroke. Thrombectomy is a relatively new but very effective and potentially life-saving therapy for the treatment for acute ischemic stroke this is where the stroke is caused by a blood clot in a major blood vessel in the brain. You may also be given aspirin or other anti-platelet medicines to reduce the stickiness of your blood and stop clots forming. However, thrombolysis is not suitable for everyone. This is why it is so important to get to hospital immediately because even within this 4.5hrs, the more time passes the less effective it is. This drug treatment is only effective if received quickly (less than 4.5 hours of a stroke starting). The drug aims to dissolve the clot and restore the blood flow to the brain. ![]() ![]() ![]() Some ischaemic strokes can be treated by thrombolysis also known as a clot busting drug. There are two main treatments for ischaemic stroke (a blocked artery) thrombolysis and thrombectomy, and the quicker a patient receives these treatments the better their chances of making a full recovery. Treatment for stroke depends on whether the stroke is caused by a blockage in your artery (ischaemic stroke) or bleeding into your brain (haemorrhagic stroke). Resuscitation Quality Improvement (RQI) Programme.CPR Courses for Healthcare Professionals.Volunteer with our patient support services.
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